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Search Results for " liver x receptor "

20

Compounds

Cat No. Product Name Synonyms Targets
T5178 AZ876 Liver X Receptor
AZ876 is a potent, highly selective LXR agonist with Ki/EC50 of 7/6 nM and 11/73 nM for hLXRα and hLXRβ respectively.
T1801 SR9243 Liver X Receptor
SR9243, an LXR inverse agonist, can induce LXR-corepressor interaction; shows anticancer activity and selectively targets the lipogenesis and Warburg effect.
T16930 SR9238 Liver X Receptor
SR9238 is a synthetic agonist of liver X receptor inverse (IC50s: 214 nM and 43 nM for LXRα and LXRβ, respectively).
T15427 GSK2033 Liver X Receptor
GSK2033 is an antagonist of LXR (pIC50s: 7 and 7.4 for LXRα or LXRβ, respectively).
T7529 Yamogenin Others
Yamogenin is a diastereomer of diosgenin, which we have identified as the compound responsible for the anti-hyperlipidemic effect of fenugreek.
T2768 Saikosaponin A NF-κB , Antibacterial , Liver X Receptor
Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-in ammatory, immunomodulatory, and anti-bacterial activities. It can effectively attenuate neuropath...
T27478 GSK3987 Liver X Receptor
GSK3987 is an LXR ligand. GSK3987 recruits the steroid receptor coactivator-1 to human LXRalpha and LXRbeta with EC50s of 40 nM.
T7768 RGX-104 RGX-104 free Acid Liver X Receptor
RGX-104 (RGX-104 free Acid) free Acid is an agonist of potent liver-X nuclear hormone receptor (LXR)
T1783 LXR-623 LXR623,WAY 252623 Liver X Receptor
LXR-623 (WAY 252623) is an orally bioavailable and highly specifical synthetic modulator of LXR.
T6310 GW3965 hydrochloride GW3965 HCl Liver X Receptor
GW3965 hydrochloride (GW3965 HCl) is an effective and specific LXR agonist for hLXRα/β (EC50: 190/30 nM).
T2601 Vidofludimus SC12267,4sc-101 Dehydrogenase , DNA/RNA Synthesis , Interleukin
Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).
T2810 (20S)-Protopanaxatriol 20(S)-APPT,g-PPT Apoptosis , Estrogen Receptor/ERR , Glucocorticoid Receptor , Estrogen/progestogen Receptor , Liver X Receptor
(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid receptor.
TQ0274 27-Hydroxycholesterol 25(R)-27-hydroxy Cholesterol Estrogen/progestogen Receptor , Liver X Receptor
27-Hydroxycholesterol (25(R)-27-hydroxy Cholesterol) is a selective modulator of estrogen receptor and an agonist of the liver X receptor.
T5128 RGX-104 hydrochloride SB742881,RGX-104 HCl Liver X Receptor
RGX-104 hydrochloride (SB742881) is a liver X receptor (LXR) agonist with potential immunomodulating and antineoplastic activities. It modulates innate immunity via transcriptional activation of the ApoE gene.
T3970 BMS-779788 XL652,EXEL04286652,XL 652,XL-652,BMS-788 Liver X Receptor
BMS-779788 (XL-652) is an LXRα/β partial agonist (IC50: 68/14 nM).
T6690 T0901317 Apoptosis , FXR , Liver X Receptor , ROR
T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).
T16792 Rovazolac ALX-101 Liver X Receptor
Rovazolac (ALX-101) is a liver x receptor (LXR) modulator used in the study of immune system disorders and atopic dermatitis.
T63896 BE1218 Liver X Receptor
BE1218 is a liver X receptor (LXR) inverse agonist active on LXRα and LXRβ with an IC50 of 9 nM and 7 nM, respectively.
T27496 GSK9772 GSK-9772,GSK 9772
GSK9772 is a transrepression-selective liver X receptor modulators with anti-inflammatory activity.
T71756 24(S),25-Epoxycholesterol
24(S),25-Epoxycholesterol is an oxysterol agonist of the liver X receptor.
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